Coffee Polyphenols Change the Expression of STAT5B and ATF-2 Modifying Cyclin D1 Levels in Cancer Cells
Table 6
Common differentially expressed genes in HT29 treated-cells.
Gene symbol
FC absolute ICC
value
Regulation
FC absolute CA
value
Regulation
FST
1.343
0.025
Up
1.375
0.022
Up
SULT1B1
1.349
0.018
Up
1.304
0.020
Up
EPOR
1.372
0.008
Up
1.321
0.021
Up
HINT3
2.410
0.040
Up
2.607
0.033
Up
STAT5B
1.312
0.007
Up
1.334
0.012
Up
GLS
1.335
0.001
Down
1.370
0.001
Down
PPP3R1
1.397
0.023
Down
1.423
0.026
Down
ATF2
1.481
0.005
Down
1.354
0.016
Down
SLC4A7
1.314
0.029
Down
1.322
0.025
Down
MARCH3
1.330
0.016
Down
1.319
0.005
Down
TBL1XR1
1.426
0.001
Down
1.332
0.001
Down
SAP30L
1.375
0.013
Down
1.405
0.021
Down
FGD4
1.593
0.001
Down
1.523
0.027
Down
ZDHHC20
1.665
0.004
Down
1.314
0.005
Down
ZDHHC21
1.642
0.037
Down
1.318
0.016
Down
FAM76B
1.506
0.014
Down
1.325
0.037
Down
CLK4
1.326
0.049
Down
1.339
0.021
Down
Common differentially expressed genes in HT29 treated-cells with a value and a minimum fold of 1.3. Column ICC correspond to cells treated with instant caffeinated coffee and column CA corresponds to cells treated with caffeic acid. Overexpressed genes are indicated on the upper part of the table, whereas underexpressed genes are depicted in the lower part. The genes in bold, STAT5B and ATF-2, were chosen for further analysis.
