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Oxidative Medicine and Cellular Longevity
Volume 2012, Article ID 479348, 17 pages
Research Article

Insulin Resistance, Ceramide Accumulation, and Endoplasmic Reticulum Stress in Human Chronic Alcohol-Related Liver Disease

1Divisions of Gastroenterology and Neuropathology, Departments of Medicine, Pathology, Neurology, and Neurosurgery, The Liver Research Center, Rhode Island Hospital and the Warren Alpert Medical School of Brown University, Providence, RI 02903, USA
2Clinical Pharmacokinetics Research Laboratory, University of Rhode Island, Kingston, RI 02881, USA
3Pierre Galletti Research Building, Rhode Island Hospital, 55 Claverick Street, Room 419, Providence, RI 02903, USA

Received 15 October 2011; Revised 28 December 2011; Accepted 10 January 2012

Academic Editor: Florian Lang

Copyright © 2012 Lisa Longato et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Figure 1 depicts Western blot analysis results corresponding to pPERK, PERK, GRP78/Bip, CHOP, and p85 (control) expression in livers from human control and chronic alcoholic subjects.

  1. Supplementary Material