Cholesterol-Lowering Effect of Allicin on Hypercholesterolemic ICR Mice

Table 1

Food intake efficiency during allicin administration (𝑛=6).

Week	1	2	3	11	12
Controld	100 ± 2.1	100 ± 3.7	100 ± 1.4	100 ± 4.9	100 ± 6.0
5 mg/kg allicine	90.3±2.7^a	88.1±4.2	80.0±2.3^a	70.7±5.9^a	82.0±4.7
10 mg/kg allicine	54.3±0.5^b	74.2±11.7^a	68.9±1.6^b	80.5±3.1^a	80.1±4.3
20 mg/kg allicine	42.0±1.3^c	65.5±5.7^b	53.0±3.3^b	65.4±3.2^b	67.7±2.4^a
Normal (regular diet)e	89.9±12.8^a	85.6±2.6^a	82.3±4.0^a	93.4±14.8	82.7±15.9

The data are mean ± S.D. and significantly different at ^a𝑃<0.05, ^b𝑃<0.01, and ^c𝑃<0.001 by the unpaired Student's t-test.
dThe high cholesterol control group, 200 μL PBS (pH 7.4) was served instead of allicin as a negative control.
eThe results are expressed as % of the high cholesterol control.