Cardiac Response to Chronic Intermittent Hypoxia with a Transition from Adaptation to Maladaptation: The Role of Hydrogen Peroxide

Table 1

The effects of CIH on cardiac I/R-induced injuries.

Authors	Strains	Exposure time	Effects	Reference
Wang et al.	Male SD rats	4 wks	Protective effects	[1]
Ding et al	Male SD rats	42 days	Protective effects	[2–4]
Neckar et al.	Male Wistar rats	8 h/day, 5 days/wks;	Protective effects	[5]
Asemu et al.	Male Wistar rats	2 wks and 5 wks	Protective effects	[6]
Park and Suzuki	C57BL/6 mice	1, 2 wks and 4 wks	Protective effects (4 wks) Deleterious effects (1, 2 wks)	[7]
Guo et al.	male guinea pigs	28 days	Protective effects	[8]
Guo et al.	Male guinea pigs	28 days	Protective effects	[9]
Zong et al.	Dogs	20 days	Protective effects	[10]
Wang et al.	Male SD rats	14, 28 and 42 days	Protective effects	[11–13]
Joyeux-Faure et al.	Male Wistar rats	7 wks	Deleterious effects	[14]

*wks: weeks.