Research Article

Blockade of TGF- 1 Signalling Inhibits Cardiac NADPH Oxidase Overactivity in Hypertensive Rats

Figure 1

Effect of P144 on cardiac NADPH oxidase activity. Cardiac NADPH oxidase-dependent production was determined by chemiluminescence in the presence of NADPH 200 μmol/L, and it is expressed as relative light units per second (RLU/s). Histogram represents mean ± SEM ( ). V-WKY means vehicle-treated normotensive rat; P144-WKY, P144-treated WKY rat; V-SHR, vehicle-treated spontaneously hypertensive rat, P144-SHR, P144-treated SHR. *   versus the other groups.
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