Blockade of TGF- 1 Signalling Inhibits Cardiac NADPH Oxidase Overactivity in Hypertensive Rats
Figure 4
Effect of P144 on cardiac levels of nitrotyrosine (NT). (a) Levels of NT relative to α-tubulin in the rat heart. Representative western blot of the four groups of rats are shown at the upper part. Histogram represents mean ± SEM (). (b) Positive correlation of cardiac NADPH oxidase activity and levels of NT in all the rats (; ; ). RLU/s means relative light units per second. V-WKY means vehicle-treated normotensive rat; P144-WKY, P144-treated WKY rat; V-SHR, vehicle-treated spontaneously hypertensive rat; P144-SHR, P144-treated SHR. * versus the other groups.
