Figure 3: Evolution of serum adiponectin (a), CRP (b), IL-6 (c), and TNF-α (d) levels between the initial time (8 weeks old) and the final time (20 weeks old) in sedentary control and diabetic rats and in diabetic exercised rats. Data are means ± sem of eight values (rats) per group. Significant differences between sedentary diabetic and sedentary control rats: and . Significant differences between exercised diabetic and sedentary diabetic rats: . CRP, C-reactive protein; IL-6, interleukin 6; TNF-α, tumour necrosis factor alpha.