Figure 3: Histologic findings of normal skin and SEs. SEs were constructed and incubated in the presence of vitamin C, G. lucidum, or R. sachalinensis at a concentration of 1 or 10 μg/mL. Sections of SEs were hematoxylin/eosin stained. (a) normal skin, (b) control SE, (c) SE treated with vitamin C, (d) SE treated with G. l, (e) SE treated with R. s.