Figure 4: Immunohistochemical staining for integrins. The SEs were constructed and incubated in the presence of vitamin C (Vit. C), G. lucidum, or R. sachalinensis at 1 or 10 μg/mL. Sections of SEs were stained for integrin α6 (a) or integrin β1 (b). Intensity of both integrins was significantly increased by addition of Vit. C or plant extracts.