Table 4: Pharmacokinetic parameters after a single oral dose of SAC.A

Parameter AUC0–t
Tissue(mg/kg)mg·h/kg(h)

Kidney65.7169.22.1
Liver58.1103.52.2
Heart43.3118.82.1
Spleen43.3100.61.9
Lung35.194.31.3
Brain26.770.71.2

ASAC dose of 50 mg/kg. Adapted from [19].
: peak concentration at 10 min; AUC0–t : area under the plasma concentration versus time curve from time zero to the last quantifiable concentration; : elimination half-life time.