The Antioxidant Mechanisms Underlying the Aged Garlic Extract- and S-Allylcysteine-Induced Protection

Table 4

Pharmacokinetic parameters after a single oral dose of SAC.^A

Parameter	𝐶max	AUC0–t	𝑇1/2
Tissue	(mg/kg)	mg·h/kg	(h)
Kidney	65.7	169.2	2.1
Liver	58.1	103.5	2.2
Heart	43.3	118.8	2.1
Spleen	43.3	100.6	1.9
Lung	35.1	94.3	1.3
Brain	26.7	70.7	1.2

^ASAC dose of 50 mg/kg. Adapted from [19].
𝐶_max: peak concentration at 10 min; AUC_0–t : area under the plasma concentration versus time curve from time zero to the last quantifiable concentration; 𝑇_1/2: elimination half-life time.