The Natural Stilbenoid Piceatannol Decreases Activity and Accelerates Apoptosis of Human Neutrophils: Involvement of Protein Kinase C

Table 2

Effect of piceatannol on extra- and intracellular chemiluminescence of isolated human neutrophils stimulated with PMA (0.05 μmol/L) and on the chemiluminescence produced by cell-free system. The exposure to piceatannol was 30 min (extra-, intracellular) or 10 min (cell-free system). Mean ± SEM, 𝑛=3--8, ^∗𝑃≤0.05, ^∗∗𝑃≤0.01  versus Control.

Piceatannol; (µmol/L)	Inhibition of chemiluminescence (% of control)
	Extracellular	Intracellular	Cell-free system
0.01	96.89±4.05	101.72±4.34	99.43±1.19
0.1	90.73±5.80	102.40±2.16	93.77±0.55^∗
1	75.74±5.55^∗	101.29±1.96	33.60±0.13^∗∗
10	5.31±0.82^∗∗	59.95±2.51^∗∗	0.72±0.04^∗∗
100	0.01±0.01^∗∗	0.65±0.15^∗∗	0.71±0.02^∗∗