Roles of Mitochondrial Dynamics under Stressful and Normal Conditions in Yeast Cells
Figure 2
Hypothetical scheme illustrating how the mitochondrial fusion-fission cycle helps to maintain mitochondrial DNA. Rearrangements of the DNA induced by mitochondrial fission-fusion and recombination result in appearance of mutation-free mitochondrial genomes. Removal of genomes with high levels of deleterious mutations inhibits the high rate of mtDNA damage (see text for details).