Kidney and liver cytopathological features after malarial infection. Effect of malaria on renal and hepatic cytopathology. Kidney and liver sections were taken from BWF1 mice at week 32. TEM photomicrographs of the kidneys showed electron-dense deposits (arrows) in both the lupus and gamma-irradiated malaria-infected groups ((a), (c)) with marked effacement of foot processes (arrow head). The live malaria-infected group showed normal foot processes with an absence of deposits (b). The liver of a lupus mouse showing a normal structure of a hepatocyte with its nucleus, mitochondrion, and rough endoplasmic reticulum (d). Liver section from the live malaria-infected group showing swollen heterochromatic nuclei and disrupted chromatin (arrow) (e). Liver section from the gamma-irradiated malaria-infected group showing vacuolated and hypertrophic nucleoli (arrow head) (f). Original magnification 10000x.