Table 3: Catalase activity in hippocampus, striatum, frontal cortex, and cerebellum of mice treated with 5TIO1 at doses 0.1, 1, and 10 mg kg−1.

GroupsCatalase (U µg of protein−1)
HippocampusStriatumFrontal cortexCerebellum

Vehicle14.22 ± 1.5419.35 ± 0.4622.51 ± 0.3724.61 ± 0.42
5TIO1 0.133.62 ± 2.52a20.39 ± 2.7915.41 ± 2.45a33.62 ± 2.52a
5TIO1 135.94 ± 2.57a26.36 ± 4.9329.91 ± 5.54a,b35.94 ± 2.57a
5TIO1 1034.98 ± 3.24a30.52 ± 7.12a,b34.03 ± 3.32a,b,c34.98 ± 3.24a

Male mice (25–30 g, 2 month-old) were intraperitoneally treated with doses of 5TIO1 (0.1, 1, and 10 mg kg−1, , 5TIO1 groups) and the control animals with 0.05% Tween 80 dissolved in 0.9% saline ( , Vehicle). Results are expressed as means ± SD for the number of animals shown inside in parenthesis. Differences in experimental groups were determined by two-tailed Analysis of Variance (ANOVA). compared to the control group (ANOVA and -Student-Neuman-Keuls as post hoc test); compared to the 5TIO1 0.1 group (ANOVA and -Student-Neuman-Keuls as post hoc test); compared to the 5TIO1 1 group (ANOVA and -Student-Neuman-Keuls as post hoc test).