The Risk of Heart Failure and Cardiometabolic Complications in Obesity May Be Masked by an Apparent Healthy Status of Normal Blood Glucose

Figure 6

Effects of hemin on glucose tolerance, insulin resistance (HOMA-IR index), and adiponectin. Hemin therapy (a) improved glucose tolerance (IPGTT), (b) increased glucose-stimulated insulin release, (c) reduced insulin resistance, and (d) increased adiponectin. Bars represent means ± SEM; 𝑛=6 rats per group (*𝑃<0.05, **𝑃<0.01 versus ZL control; ^†𝑃<0.01 versus ZL control; ^@𝑃<0.01 versus ZF+hemin+SnMP or ZF control).

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(b)

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