Acute Hyperglycemia Abolishes Ischemic Preconditioning by Inhibiting Akt Phosphorylation: Normalizing Blood Glucose before Ischemia Restores Ischemic Preconditioning

<table>The cardioprotective effect of ischemic preconditioning disappears in HG mice, but can be recovered by normalizing blood glucose levels with insulin prior to ischemia.</table>

Oxidative Medicine and Cellular Longevity

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Figure 4

Figure 4: Acute Hyperglycemia Abolishes Ischemic Preconditioning by Inhibiting Akt Phosphorylation: Normalizing Blood Glucose before Ischemia Restores Ischemic Preconditioning 

Figure 4 | Acute Hyperglycemia Abolishes Ischemic Preconditioning by Inhibiting Akt Phosphorylation: Normalizing Blood Glucose before Ischemia Restores Ischemic Preconditioning 