Oxidative Medicine and Cellular Longevity / 2013 / Article / Fig 1

Review Article

Redox Regulation in Amyotrophic Lateral Sclerosis

Figure 1

Schematic diagram showing domain structure of PDI. Thioredoxin-like domain (orange) and domain (purple) possessing the catalytic motif, catalytically inactive domain (blue), and domain (red). Green represents the linker region which allows flexibility between domains. The C terminal domain is shown in grey followed by the ER retrieval signal KDEL.