Curcumin Protects Human Keratinocytes against Inorganic Arsenite-Induced Acute Cytotoxicity through an NRF2-Dependent Mechanism
Figure 3
mRNA expression of NRF2, NRF1, KEAP1, and some ARE-dependent genes induced by curcumin in HaCaT cells. (a) Concentration response of curcumin-induced gene expression. Cells were exposed to different concentrations of curcumin for 6 hr. (b) Time course of gene expression induced by 5 μM curcumin. The number in parentheses after each gene name is the Ct (cross-threshold) value of that gene in HaCaT cells treated with vehicle (medium). Values are mean SD. . * versus vehicle.