Resveratrol Protects the Brain of Obese Mice from Oxidative Damage

Table 1

Effect of resveratrol on the body weight and blood glucose level in lean and obese mice. The body and fat pad weight (a), blood glucose level and food intake (b) were estimated in lean and obese mice.

(a)

Parameter	Lean	Lean + Res	ob/ob	ob/ob + Res
Body weight (g)	25.1 ± 1.58	23.9 ± 1.26	49.3±6.19^a∗∗∗	47.2±4.50^bNS
Fat pad (g)	1.24 ± 0.24	1.08 ± 0.11	13.12±3.71^a∗∗∗	11.23±2.75^bNS

(b)

Parameter	Lean	Lean + Res	ob/ob	ob/ob + Res
Blood glucose (mg/dL)	124.2 ± 19.40	111.8 ± 21.24	242.2±58.1^a∗∗∗	288.4±44.4^bNS
Food intake (g/day)	4.44 ± 0.11	4.96 ± 1.61	6.58±3.24^aNS	9.56±3.28^c∗

Values are expressed as mean ± S.D. for twelve mice in each group.
Values are statistically significant at ^∗∗∗𝑃<0.001 and ^∗𝑃<0.05.
^aob/ob mice were compared with lean control mice; ^bob/ob mice were compared with ob/ob-resveratrol treated mice; ^clean mice were compared with ob/ob-resveratrol treated mice. NS represents nonsignificant.