Antigenotoxic and Apoptotic Activity of Green Tea Polyphenol Extracts on Hexavalent Chromium-Induced DNA Damage in Peripheral Blood of CD-1 Mice: Analysis with Differential Acridine Orange/Ethidium Bromide Staining

Table 2

Averages of viable cells (apoptotic and nonapoptotic) and nonviable cells (apoptotic and nonapoptotic) in peripheral blood of mice treated with polyphenol extract of green tea and CrO₃.

Treatment	Dose(mg/kg)	𝑛	Nonapoptotic viable cells* (mean ± S.D.)	Apoptotic viable cells* (mean ± S.D.)	Apoptotic nonviable cells* (mean ± S.D.)	Nonapoptotic nonviable cells* (mean ± S.D.)
Control	0	5	197.2±2.2	2.4±1.8	0.0±0.0	0.4±0.9
Polyphenol extracts of green tea	30	5	192.8±4.9	6.0±4.1	0.8±1.3	0.4±0.6
CrO3	20	5	189.2±3.3^a	10.2±3.6^c	0.2±0.5	0.4±0.6
Polyphenol extracts of green tea–CrO3	30–20	5	187.2±6.3^b	12.8±6.3^d	0.0±0.0	0.0±0.0

^a𝑃<0.05 versus control; ^b𝑃<0.01 versus control; ^c𝑃<0.04 versus control; ^d𝑃<0.007 versus control.
*Evaluation in 200 cells.