Oxidative Medicine and Cellular Longevity / 2013 / Article / Fig 4

Research Article

Effects of Endothelial Progenitor Cell-Derived Microvesicles on Hypoxia/Reoxygenation-Induced Endothelial Dysfunction and Apoptosis

Figure 4

Effects of EPC-MVs on miR126 expression, ROS production, and apoptosis in H/R hb-ECs. (a) Representative images showing the merging of PKH26 labeled EPC-MVs with hb-ECs (red: PKH26; blue: DAPI). Scale bar: 100 μm. (b) miR126 expression in H/R hb-ECs cocultured with aEPC-MVs or sEPC-MVs. (c) ROS production of H/R hb-ECs cocultured with aEPC-MVs or sEPC-MVs. (d) Apoptosis of H/R hb-ECs cocultured with aEPC-MVs or sEPC-MVs. * , versus vehicle; + , versus sEPC-MVs or aEPC-MVs; # , versus sEPC-MVs or RNase-sEPC-MVs; /group.
572729.fig.004a
(a)
572729.fig.004b
(b)
572729.fig.004c
(c)
572729.fig.004d
(d)

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.