Potentiation of Antibiofilm Activity of Amphotericin B by Superoxide Dismutase Inhibition
Figure 1
Effect of N-N′-diethyldithiocarbamate (DDC) on AmB-tolerant cells in C. albicans CA-IF100 biofilms. Biofilms were treated with or without (/) 1 μM AmB in presence or absence (−) of 10 mM DDC. After 24 hours, biofilms were washed with PBS and the percentage survival of C. albicans cells, relative to the control treatment (2% DMSO), was determined by plating the biofilm cells on YPD plates. Data represent the mean and SEM for one representative experiment out of two, each consisting of triplicate measurements. ***.
