The Potential Role of Azadirachta indica Treatment on Cisplatin-Induced Hepatotoxicity and Oxidative Stress in Female Rats

Table 1

Protective effects of methanolic neem leaves extract on cisplatin (CDDP) induced alternation in liver function of rats.

Groups	ALT (IU/L)	AST (IU/L)	γGT activity (IU/L)	ALP (IU/L)	Total bilirubin (mg/dL)
Con	85.23±3.98	68.98±1.90	31.66±1.15	4.26±0.38	2.78±0.16
CDDP	121.82±3.13^a	90.32±1.19^a	54.22±1.88^a	6.82±0.30^a	5.87±0.20^a
MNLE	83.59±1.23	72.09±2.90	29.60±1.24	3.84±0.28	2.57±0.08
CDDP-N	86.28±1.91^b	70.88±1.67^b	36.33±1.37^b	4.99±0.25^b	3.13±0.22^b

Values are means ± SEM (𝑛=6).
^a𝑃<0.05, significant change with respect to Control; ^b𝑃<0.05, significant change with respect to CDDP for Duncan's post hoc test.