Skin Injuries Reduce Survival and Modulate Corticosterone, C-Reactive Protein, Complement Component 3, IgM, and Prostaglandin E₂ after Whole-Body Reactor-Produced Mixed Field (n + 𝜸-Photons) Irradiation

Figure 3

Skin injuries altered CRP responses to radiation. 𝑁 = 3–6 per group and per time point. The control CRP concentration was 4.0±0.1 μg/mL. (a) Skin wound trauma transiently decreased serum CRP concentrations at days 2 and 3, then increased it at days 4–7, reduced to baseline, and rose again at days 16–24. *𝑃<0.05; **𝑃<0.01 versus control group. (b) Skin burn trauma increased serum CRP concentrations at days 1, 5, and 20 after irradiation. *𝑃<0.05; **𝑃<0.01 versus control group. wnd: wounding; brn: burning; rad: radiation at 3 Gy (n/n + 𝛾 = 0.94).

(a)

(b)