Skin Injuries Reduce Survival and Modulate Corticosterone, C-Reactive Protein, Complement Component 3, IgM, and Prostaglandin E₂ after Whole-Body Reactor-Produced Mixed Field (n + 𝜸-Photons) Irradiation

Figure 4

Skin injuries altered C3 responses to radiation.𝑁 = 3–5 per group and per time point. (a) Skin wound trauma enhanced and sustained the radiation-induced increase in serum C3 concentrations. The control C3 concentration was 325±10 μg/mL. *𝑃<0.05; **𝑃<0.01; ***𝑃<0.001 versus control group. (b) Skin burn trauma increased and sustained serum C3 concentrations after irradiation. The control C3 concentration was 310±11 μg/mL. *𝑃<0.05; **𝑃<0.01, ***𝑃<0.001 versus control group. wnd: wounding; brn: burning; rad: radiation at 3 Gy (n/n + 𝛾 = 0.94).

(a)

(b)