Skin Injuries Reduce Survival and Modulate Corticosterone, C-Reactive Protein, Complement Component 3, IgM, and Prostaglandin E₂ after Whole-Body Reactor-Produced Mixed Field (n + 𝜸-Photons) Irradiation

Figure 5

Skin injuries enhanced the radiation-induced decrease in IgM concentrations. 𝑁=6 per group and per time point. (a) Skin wound trauma enhanced and sustained the radiation-induced decrease in serum IgM concentrations. *𝑃<0.05; **𝑃<0.01; ***𝑃<0.001 versus control group. (b) Skin burn trauma decreased and sustained serum IgM concentrations after irradiation. *𝑃<0.05; **𝑃<0.01, ***𝑃<0.001 versus control group. wnd: wounding; brn: burning; rad: radiation at 3 Gy (n/n + 𝛾 = 0.94).

(a)

(b)