Therapeutic Effect of MG132 on the Aortic Oxidative Damage and Inflammatory Response in OVE26 Type 1 Diabetic Mice
Effects of MG132 on aortic expression of Nrf2 and its downstream genes, examined by immunohistochemical staining for the expression of Nrf2 (red) (a) in aortic tunica media with semi-quantitative analysis (b). Real-time PCR was used to measure the expression of Nrf2 downstream genes at mRNA levels: NQO1 (c), HO-1 (d), and SOD-1 (e). Data were presented as means ± SD (). versus control; versus DM. Bar = 50 μM.