Research Article

Therapeutic Effect of MG132 on the Aortic Oxidative Damage and Inflammatory Response in OVE26 Type 1 Diabetic Mice

Figure 6

Effects of MG132 on aortic expression of Nrf2 and its downstream genes, examined by immunohistochemical staining for the expression of Nrf2 (red) (a) in aortic tunica media with semi-quantitative analysis (b). Real-time PCR was used to measure the expression of Nrf2 downstream genes at mRNA levels: NQO1 (c), HO-1 (d), and SOD-1 (e). Data were presented as means ± SD ( ). versus control;   versus DM. Bar = 50 μM.
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