N-n-Butyl Haloperidol Iodide Ameliorates Cardiomyocytes Hypoxia/Reoxygenation Injury by Extracellular Calcium-Dependent and -Independent Mechanisms

Figure 3

Effects of F₂, Verapamil, and PKCα inhibitor and activator on p-PKCα, total PKCα, p-ERK1/2, total ERK1/2, and Egr-1 expression in extracellular-calcium-containing myocardial H/R by western-blot assay. (a) p-PKCα and total PKCα protein levels; (b) p-ERK1/2 and total ERK1/2 protein levels; (c) Egr-1 protein levels. All values are expressed as mean ± S.E.M. of at least six individual experiments. ^∗𝑃<0.05 versus CaCon group; ^#𝑃<0.05 versus CaH/R group; ^†𝑃<0.05 versus CaH/R+F₂ group.

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