Research Article

N-n-Butyl Haloperidol Iodide Ameliorates Cardiomyocytes Hypoxia/Reoxygenation Injury by Extracellular Calcium-Dependent and -Independent Mechanisms

Table 4

Effects of PKA inhibitor and activator on LDH leakage of cardiomyocyte in extracellular-calcium-free H/R ( ).

Group LDH (U/mL)

0CaCon952.70 ± 32.02
0CaH/R1378.33 ± 72.26*
0CaH/R + H891389.14 ± 71.65*
0CaH/R + Forskolin1338.78 ± 51.68*

LDH: lactate dehydrogenase; PKA: protein kinase A; H/R: hypoxia/reoxygenation.* versus 0CaCon group.