Research Article
Leptin Level and Oxidative Stress Contribute to Obesity-Induced Low Testosterone in Murine Testicular Tissue
Table 4
MDA, H
2O
2, T-AOC, GSH, SOD, GSH-Px, and CAT level of testis tissue in 8 weeks and 19 weeks (
± SD).
| | Group | | MDA (nmol/mgprot) | T-AOC (U/mgprot) | SOD (U/mgprot) | GSH (mgGSH/gprot) | H2O2 (mmol/gprot) | CAT (U/mgprot) | GSH-Px (U/mgprot) | NO (umol/gprot) |
| 8 weeks | DIO | 12 | 0.38 ± 0.20** | 1.03 ± 0.15 | 50.98 ± 10.26 | 12.78 ± 1.80 | 16.55 ± 3.73* | 1.07 ± 0.31* | 15.98 ± 3.10 | 0.32 ± 0.15** | DIO-R | 12 | 0.24 ± 0.12* | 1.04 ± 0.20 | 49.71 ± 10.13 | 12.88 ± 1.66 | 16.75 ± 4.65* | 0.98 ± 0.41* | 13.71 ± 3.69 | 0.32 ± 0.10** | Control | 12 | 0.21 ± 0.07 | 0.94 ± 0.13 | 53.45 ± 14.64 | 13.09 ± 1.98 | 10.82 ± 1.16 | 1.52 ± 0.25 | 15.93 ± 3.36 | 0.19 ± 0.03 |
| 19 weeks | DIO | 12 | 0.89 ± 0.24* | 0.73 ± 0.23* | 71.46 ± 10.63 | 13.38 ± 1.20* | 16.68 ± 4.35* | 0.28 ± 0.08* | 26.26 ± 6.34* | 0.32 ± 0.13** | DIO-R | 12 | 1.12 ± 0.51** | 0.77 ± 0.24 | 76.97 ± 16.74 | 12.84 ± 2.81 | 15.58 ± 2.98 | 0.15 ± 0.07** | 26.03 ± 6.34* | 0.27 ± 0.06* | Control | 12 | 0.47 ± 0.12 | 0.94 ± 0.16 | 71.94 ± 7.56 | 10.92 ± 2.48 | 12.62 ± 2.69 | 0.53 ± 0.24 | 33.52 ± 5.42 | 0.18 ± 0.05 |
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Note. Data are mean ± SD. and denote statistical significance compared with control group.
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