Research Article

Leptin Level and Oxidative Stress Contribute to Obesity-Induced Low Testosterone in Murine Testicular Tissue

Table 4

MDA, H2O2, T-AOC, GSH, SOD, GSH-Px, and CAT level of testis tissue in 8 weeks and 19 weeks (   ± SD).

Group MDA
(nmol/mgprot)
T-AOC
(U/mgprot)
SOD
(U/mgprot)
GSH
(mgGSH/gprot)
H2O2
(mmol/gprot)
CAT
(U/mgprot)
GSH-Px
(U/mgprot)
NO
(umol/gprot)

8 weeksDIO120.38 ± 0.20**1.03 ± 0.1550.98 ± 10.2612.78 ± 1.8016.55 ± 3.73*1.07 ± 0.31*15.98 ± 3.100.32 ± 0.15**
DIO-R120.24 ± 0.12*1.04 ± 0.2049.71 ± 10.1312.88 ± 1.6616.75 ± 4.65*0.98 ± 0.41*13.71 ± 3.690.32 ± 0.10**
Control120.21 ± 0.070.94 ± 0.1353.45 ± 14.6413.09 ± 1.9810.82 ± 1.161.52 ± 0.2515.93 ± 3.360.19 ± 0.03

19 weeksDIO120.89 ± 0.24*0.73 ± 0.23*71.46 ± 10.6313.38 ± 1.20*16.68 ± 4.35*0.28 ± 0.08*26.26 ± 6.34*0.32 ± 0.13**
DIO-R12 1.12 ± 0.51**0.77 ± 0.2476.97 ± 16.7412.84 ± 2.8115.58 ± 2.980.15 ± 0.07**26.03 ± 6.34*0.27 ± 0.06*
Control120.47 ± 0.120.94 ± 0.1671.94 ± 7.5610.92 ± 2.4812.62 ± 2.690.53 ± 0.2433.52 ± 5.420.18 ± 0.05

Note. Data are mean ± SD. and denote statistical significance compared with control group.