Effects of Paracetamol on NOS, COX, and CYP Activity and on Oxidative Stress in Healthy Male Subjects, Rat Hepatocytes, and Recombinant NOS
Figure 5
Effect of a 3 g single oral dose of paracetamol on serum cis-epoxyoctadecanoic acid (cis-EpOA) and 15()-8-iso-PGF2α in four healthy volunteers (time zero and baseline value are indicated by dashed lines). Data are shown as mean ± SEM. Note the logarithmic scale on the -axis. Only the 2.5 h concentration of cis-EpOA was statistically significantly different () compared to the baseline.
