Lithium Chloride Suppresses Colorectal Cancer Cell Survival and Proliferation through ROS/GSK-3β/NF-κB Signaling Pathway

Figure 6

Effect of LiCl on the expression of NF-κB, Bal-2, and survivin protein and mRNA levels. (a) The protein expression of NF-κB, Bal-2, and survivin. (b-c) The mRNA levels of NF-κB, Bal-2, and survivin were analyzed by real-time PCR. The SW480 cells treated with vehicles (PBS) and different concentrations of LiCl (10 mM, 20 mM, 40 mM, and 60 mM), respectively. Data are expressed as mean ± SEM for at least three individual experiments. ^∗𝑃<0.05 and ^∗∗𝑃<0.01 versus Control group.

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