Clinical Study

Increased Growth Factors Play a Role in Wound Healing Promoted by Noninvasive Oxygen-Ozone Therapy in Diabetic Patients with Foot Ulcers

Figure 2

Wound size reduction (cm², ). Before treatment there was no significant difference in ulcer area between the ozone group and the control group ( versus , ). After treatment the ulcer area in both groups was significantly smaller than before. The wound area reduction ( area) was significantly more in the ozone group than in the control group (6.84 ± 0.62 versus 3.19 ± 0.65 cm2, ). , .