Clinical Study

Increased Growth Factors Play a Role in Wound Healing Promoted by Noninvasive Oxygen-Ozone Therapy in Diabetic Patients with Foot Ulcers

Figure 4

Changes of growth factors in wound exudates at 0, 3, 7, and 11 d after treatment. (a) VEGF levels (pg/mL) in wound exudates significantly increased in both groups after treatment. (b) TGF-β levels (pg/mL) in wound exudates significantly increased in both groups at 7 d and 11 d after treatment. And at 11 d ozone group has higher TGF-β level than control. (c) PDGF levels (pg/mL) in wound exudates significantly increased at 7 and 11 d after treatment in both groups with higher levels in ozone group than in control. versus the same group at day 0. versus control group at the same day.
273475.fig.004a
(a)
273475.fig.004b
(b)
273475.fig.004c
(c)