Increased Growth Factors Play a Role in Wound Healing Promoted by Noninvasive Oxygen-Ozone Therapy in Diabetic Patients with Foot Ulcers
Figure 4
Changes of growth factors in wound exudates at 0, 3, 7, and 11 d after treatment. (a) VEGF levels (pg/mL) in wound exudates significantly increased in both groups after treatment. (b) TGF-β levels (pg/mL) in wound exudates significantly increased in both groups at 7 d and 11 d after treatment. And at 11 d ozone group has higher TGF-β level than control. (c) PDGF levels (pg/mL) in wound exudates significantly increased at 7 and 11 d after treatment in both groups with higher levels in ozone group than in control. versus the same group at day 0. versus control group at the same day.