BMP-2 Overexpression Augments Vascular Smooth Muscle Cell Motility by Upregulating Myosin Va via Erk Signaling

Table 2

BMP-2 increased uni- and multicellular population motility.

	Control	50 ng/mL	100 ng/mL	250 ng/mL	500 ng/mL
Signal cell movement distance (um/15 min)	0.112+0.01	0.134+0.01	0.165+0.02	0.202+0.05	0.221+0.028
𝑃 value with ctrl		0.08	0.0021*	0.0003*	0.00032*
Populations movement distance (um/24 h)	40.5+10.2	48.0+12.6	56.9+10.3	76.7+9.6	80.1+13.2
𝑃 value with ctrl		0.32	0.034*	0.0004*	0.0007*

Compared to control group, Student’s test: *𝑃<0.01.