Oxidative Damage to Nucleic Acids and Benzo(a)pyrene-7,8-diol-9,10-epoxide-DNA Adducts and Chromosomal Aberration in Children with Psoriasis Repeatedly Exposed to Crude Coal Tar Ointment and UV Radiation

Table 2

The content of selected PAHs in pharmaceutical grade crude coal tar (CCT).

PAHs	IARC^a	mg/g	PAHs	IARC^a	mg/g
Benzo(a)pyrene	1	0.008	Acenaphthene	3	0.104
Dibenz(a,h)anthracene	2A	0	Anthracene	3	2.494
Benz(a)anthracene	2B	0	Benzo(g,h,i)perylene	3	0
Benzo(b)fluoranthene	2B	0	Fluoranthene	3	0.413
Benzo(k)fluoranthene	2B	0	Fluorene	3	0.299
Chrysene	2B	0.028	Phenanthrene	3	2.520
Indeno(1,2,3-c,d)pyrene	2B	0	Pyrene	3	0.241
Naphthalene	2B	3.286	Acenaphthylene	—	0.153

^aClassification according to WHO (IARC Monographs on the Evaluation of Carcinogenic Risk to Humans, Volumes 1–109, 2014):
Group 1: the agent is carcinogenic to humans;
Group 2A: the agent is probably carcinogenic to humans;
Group 2B: the agent is possibly carcinogenic to humans;
Group 3: the agent is not classifiable as to its carcinogenicity to humans.