Research Article
Oxidative Modification of Proteins in Pediatric Cystic Fibrosis with Bacterial Infections
Table 2
Clinical characteristics and oxidative stress markers of the patients studied.
| | Parameter | Healthy subjects | Pseudomonas aeruginosa | Staphylococcus aureus |
| | Relative fluorimetric results | | | | | AGE (a.u./mg protein) |
(2.57–3.81) |
(3.34–5.89) |
(3.5–5.28) | | Dityrosine (a.u./mg protein) |
(2.29–3.38) |
(2.88–5.22) |
(3.09–5.28) | | Formylkynurenine (a.u./mg protein) |
(2.49–3.83) |
(3.21–5.87) |
(3.50–5.47) | | Kynurenine (a.u./mg protein) |
(3.55–4.51) |
(3.36–5.8) |
(3.24–5.91) | | Tryptophan (a.u./mg protein) |
(544.2–658.27) |
(371.66–497.16) |
(385.38–516.86) | | Modification of proteins | | | | | Carbonyl protein (nmol/mg protein) |
(0.76–1.15) |
(0.96–2.93) |
(1.28–2.33) | | Thiol groups (nmol/mg protein) |
(18.6–20.49) |
(12.6–19.05) |
(11.19–19.83) | | AOPP (nmol/mg protein) |
(141.09–183.32) |
(137.18–318.19) |
(139.71–293.77) | | Amadori products (nmol/mg protein) |
(1416.4–1675.38) |
(1234.74–2878.33) |
(1351.38–1762.19) | | Activity of erythrocyte enzymes | | | | | Glutathione S-transferase (U/g Hb) |
(0.55–0.94) |
(1.43–3.99) |
(1.49–3.91) | | Catalase (U/mg Hb) |
(0.29–0.39) |
(0.19–0.37) |
(0.22–0.33) | | Superoxide dismutase (U/g Hb) |
(1056.4–1296.93) |
(690.8–1671.34) |
(859.38–1387.81) | | Total antioxidant capacity (nmol/mg protein) |
(14.22–18.44) |
(18–30.67) |
(17.84–21.77) | | Level of nitric oxide eNO (ppb) |
(5.3–22.4) |
(6.4–20.6) |
(5.6–16.8) |
|
|
Data are shown as means ± SD (range).
.
|
