Oxidative Medicine and Cellular Longevity / 2014 / Article / Tab 1

Research Article

Antiosteoporotic Effect of Combined Extract of Morus alba and Polygonum odoratum

Table 1

Effect of various doses of the combined extract of Morus alba and Polygonum odoratum leaves on the oxidative stress marker in the bone.

Rats groups
()
MDA
(nM/mg protein)
(mean ± SEM)
SOD
(nM/mg protein)
(mean ± SEM)
GPx
(unit/mg protein)
(mean ± SEM)

Control0.076 ± 0.0100.161 ± 0.0231.769 ± 0.186
Sham + vehicle0.078 ± 0.0150.130 ± 0.0171.657 ± 0.272
OVX + vehicle0.126 ± 0.018##aa0.070 ± 0.015###aa0.869 ± 0.108#a
OVX + genistein0.092 ± 0.008*0.117 ± 0.008*1.162 ± 0.615
OVX + D10.060 ± 0.004***0.100 ± 0.0071.555 ± 0.163**
OVX + D20.077 ± 0.017**0.111 ± 0.013*1.497 ± 0.169**
OVX + D30.075 ± 0.015**0.157 ± 0.010***1.143 ± 0.071

(/group) *,**,*** value < 0.05, 0.01, and 0.001, respectively, compared to OVX: vehicle treated group; #,##,### value < 0.05, 0.01, and 0.001, respectively, compared to control group; a,aa value < 0.01, 0.001, respectively, compared to sham operation group. D1: the combined extract at dose of 5 mg·kg−1 BW, D2: the combined extract at dose of 150 mg·kg−1 BW, and D3: the combined extract at dose of 300 mg·kg−1 BW.

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