Antiosteoporotic Effect of Combined Extract of Morus alba and Polygonum odoratum

Table 1

Effect of various doses of the combined extract of Morus alba and Polygonum odoratum leaves on the oxidative stress marker in the bone.

Rats groups; ()	MDA; (nM/mg protein); (mean ± SEM)	SOD; (nM/mg protein); (mean ± SEM)	GPx; (unit/mg protein); (mean ± SEM)
Control	0.076 ± 0.010	0.161 ± 0.023	1.769 ± 0.186
Sham + vehicle	0.078 ± 0.015	0.130 ± 0.017	1.657 ± 0.272
OVX + vehicle	0.126 ± 0.018^##aa	0.070 ± 0.015^###aa	0.869 ± 0.108^#a
OVX + genistein	0.092 ± 0.008^*	0.117 ± 0.008^*	1.162 ± 0.615
OVX + D1	0.060 ± 0.004^***	0.100 ± 0.007	1.555 ± 0.163^**
OVX + D2	0.077 ± 0.017^**	0.111 ± 0.013^*	1.497 ± 0.169^**
OVX + D3	0.075 ± 0.015^**	0.157 ± 0.010^***	1.143 ± 0.071

(/group) ^*,**,*** value < 0.05, 0.01, and 0.001, respectively, compared to OVX: vehicle treated group; ^#,##,### value < 0.05, 0.01, and 0.001, respectively, compared to control group; ^a,aa value < 0.01, 0.001, respectively, compared to sham operation group. D1: the combined extract at dose of 5 mg·kg⁻¹ BW, D2: the combined extract at dose of 150 mg·kg⁻¹ BW, and D3: the combined extract at dose of 300 mg·kg⁻¹ BW.