A Review on Hemeoxygenase-2: Focus on Cellular Protection and Oxygen Response
Catalytic reaction of HOs and BVR. The sequence is shown in three stages, separated by three well-defined intermediates: ferric-hydroperoxide, α-meso-hydroxyheme, and α-verdoheme. The final products of the reaction are CO, biliverdin IXα, and Fe2+. Biliverdin IXα is then reduced by BVR.
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.