Oxidative Medicine and Cellular Longevity / 2014 / Article / Fig 2

Research Article

Mitochondria-Targeted Antioxidant Prevents Cardiac Dysfunction Induced by Tafazzin Gene Knockdown in Cardiac Myocytes

Figure 2

Mito-Tempo blocked the enhanced mitochondrial ROS production induced by tafazzin knockdown. NVMs were transduced with the shRNA adenovirus overnight, treated with mito-Tempo for 24 h and tested for ROS. (a) Representative picture of mitochondrial ROS. Each panel represents 15 images from 3 separate experiments. Scale bars, 100 μm. (b) Quantitative analysis of panel A MitoSOX red staining. Data represent mean ± SE of 3 separate experiments. versus SCR treated with vehicle. versus Taz knockdown cells treated with vehicle.

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