Epicatechin and Catechin Modulate Endothelial Activation Induced by Platelets of Patients with Peripheral Artery Disease
Figure 3
HUVEC eNOS activation and NOx production. Densitometric analysis of P-eNOS/total eNOS ratio (a) and NOx production (b) in HUVEC incubated with EGF (white bar), supernatant of activated platelets from HS (SAHS) (dark gray bars), supernatant of activated platelets from PAD patients (SAPAD) (black bar), and supernatant of activated platelets from PAD patients (SAPAD), pretreated with scalar doses of epicatechin (0.1–10 μM) plus catechin (0.1–10 μM) (mix) (light gray bars) (). A representative western blot analysis of eNOS phosphorylation (a).
