Research Article

Antioxidant Bioactivity of Samsum Ant (Pachycondyla sennaarensis) Venom Protects against CCL4-Induced Nephrotoxicity in Mice

Table 1

Histological score of the pathological changes in the renal tissues in mice treated just with CCL4 and those treated with CCL4 and different doses of SAV.

Histopathological lesionsOedematous glomeruli
HaemorrhageInfiltration of inflammatory cellsHyaline castsDisintegrated nucleus

Control
CCl4-mice+++++++++++++++
100 µg/kg SAV + CCl4+
200 µg/kg SAV + CCl4+
300 µg/kg SAV + CCl4+++
400 µg/kg SAV + CCl4++++

−: a lack of structural changes; +: slight structural changes; ++: moderate structural changes; +++: severe structural changes.