Promoter Hypermethylation and Suppression of Glutathione Peroxidase 3 Are Associated with Inflammatory Breast Carcinogenesis
Figure 1
GPX3 protein is downregulated in IBC. Microscopic images representative of IHC stain of GPX3 (brown color) in (a) normal breast tissues showing moderate to marked intensity of GPX3, (b) non-IBC tissue sections showing mild intensity of GPX3, and (c) IBC tissue sections with no immunostaining of GPX3 by carcinoma cells within tumor emboli (magnification: upper panel, 10x; lower panel, 40x).
