Research Article
Promoter Hypermethylation and Suppression of Glutathione Peroxidase 3 Are Associated with Inflammatory Breast Carcinogenesis
Table 1
Patients’ clinical and pathological data.
| | Characteristics | Non-IBC
(%) | IBC
(%) | value |
| | Age | | | | | Mean ± SE | | | | | ≤50 | 7 (35) | 18 (90) | <0.001* | | >50 | 13 (65) | 2 (10) | | Tumor size** | | | | | Mean ± SE | | | | | ≤2 cm | 1 (5) | 0 | >0.05 | | >2 cm | 19 (95) | 18 (90) | | Tumor grade | | | | | G2 | 15 (75) | 14 (70) | >0.05 | | G3 | 5 (25) | 6 (30) | | Lymph node status** | | | | | Positive | 17 (85) | 18 (90) | >0.05 | | Negative | 3 (15) | 0 | | Number of lymph nodes** | | | | | ≤6 | 16 (80) | 6 (33.3) | <0.01* | | >6 | 4 (20) | 12 (66.7) | | Lymphovascular invasion | | | | | Positive | 2 (10) | 14 (70) | <0.001* | | Negative | 18 (90) | 6 (30) | | Dermal lymphatic emboli | | | | | Positive | 2 (10) | 18 (90) | <0.001* | | Negative | 18 (90) | 2 (10) | | ER status | | | | | Positive | 7 (35) | 6 (30) | >0.05 | | Negative | 13 (65) | 14 (70) | | PR status | | | | | Positive | 9 (45) | 7 (35) | >0.05 | | Negative | 11 (55) | 13 (65) | | HER-2 status | | | | | Positive | 2 (10) | 4 (20) | >0.05 | | Negative | 18 (90) | 16 (80) |
|
|
Significant value calculated by Student’s -test.
in IBC patients.
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