CAT, GPX1, MnSOD, GSTM1, GSTT1, and GSTP1 Genetic Polymorphisms in Chronic Myeloid Leukemia: A Case-Control Study

Table 2

Findings of various studies regarding leukemic risk and GSTT1, GSTM1, and GSTP1 Ile105Val polymorphisms.

	Association with leukemic risk (OR, 95% CI, value, study)	No association with leukemic risk (OR, 95% CI, value, study)
Combined GSTM1 and GSTT1 null genotypes	OR = 9.47, 95% CI = 3.61–24.87, , Özten et al. [11]	—
	OR = 1.79, 95 % CI = 1.24–2.58, , He et al. [8]
	OR = 3.09, 95% CI = 1.12–8.52, , Bhat et al. [9]
GSTT1 null genotypes	OR = 1.57, 95 % CI = 1.15–2.14, , He et al. [8]	OR = 1.34, 95% CI = 0.75–2.40, , Löffler et al. [12]
	OR = 2.12, 95% CI = 1.12–4.02; , Bhat et al. [9]
	OR = 3.53, 95% CI = 2.08–6.00, , Özten et al. [11]
	OR = 2.82, 95% CI = 1.58–5.05, , Taspinar et al. [20]
	OR = 1.64, 95% CI = 1.03–2.63, , Zhou et al. [21]
GSTM1 null genotypes	—	OR = 0.94, 95% CI = 0.81–1.08, , He et al. [8]
		OR = 1.327, 95% CI = 0.73–2.40; , Bhat et al. [9]
		OR = 1.11, 95% CI = 0.69–1.80, , Özten et al. [11]
		OR = 0.92, 95% CI = 0.58–1.46, , Löffler et al. [12]
		OR = 1.20; 95% CI = 0.78–1.85; , Zhou et al. [21]
GSTP1 Ile105Val genotypes	, Sailaja et al. [10]	, Karkucak et al. [7]
		OR = 1.64; 95% CI = 1.03–2.63; , Zhou et al. [21].