Olive (Olea europaea) Leaf Extract Induces Apoptosis and Monocyte/Macrophage Differentiation in Human Chronic Myelogenous Leukemia K562 Cells: Insight into the Underlying Mechanism
Figure 2
(a) Effect of Chemlali Olive Leaf Extract (COLE) on the proliferation of K562 cells. The cells were treated with various concentrations (50, 75, 100, 125, and 150 μg/mL) of COLE for 24, 48, and 72 h. Cell proliferation was measured by MTT assay. Control represents cells treated with 0.3% ethanol in medium. Results are represented as the mean ± SD of three independent experiments. *, **: significantly different from the control ( and , resp.). (b) Morphological observations of K562 cells after treatment with various concentrations of Chemlali Olive Leaf Extract (COLE) for 72 h. Cells were observed under a phase contrast microscope at 100x magnification. Scale bars represent 100 μm.
