Olive (Olea europaea) Leaf Extract Induces Apoptosis and Monocyte/Macrophage Differentiation in Human Chronic Myelogenous Leukemia K562 Cells: Insight into the Underlying Mechanism
Figure 5
Expression of differentiation markers on K562 cells treated with Chemlali Olive Leaf Extract (COLE) up to 6 days. Cells were treated with 50, 100, and 150 μg/mL of COLE and incubated for different periods. Control cells were treated with ethanol at a final concentration of 0.3%. Expression of cell surface markers was detected by flow cytometry. (a) Expression of CD14 (monocyte/macrophage specific marker). (b) Expression of CD11b (granulocyte/monocyte specific marker). (c) Expression of CD41 (megakaryocyte specific marker). (d) Expression of glycophorin A (GPA) (erythrocyte specific marker). Results are represented as the mean ± SD of three independent experiments. *, **: significantly different from the control at and , respectively.
