Research Article

TSG (2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside) from the Chinese Herb Polygonum multiflorum Increases Life Span and Stress Resistance of Caenorhabditis elegans

Table 2

Summary of the life span analyses of wild type nematodes (Figure 6(b)) and daf-16 loss-of-function mutants (strain CF1038) (Figure 7).

Wild type Adult life span
TreatmentMeanMedian (censored) versus DMSO (log-rank)

DMSO 17.39 ± 0.5618.00 ± 0.61121 (14)
Quercetin (100 µM)20.68 ± 0.6723.00 ± 1.00118 (17)<0.001
Resveratrol (100 µM)21.31 ± 0.5022.00 ± 0.71129 (6)<0.001
TSG (100 μM)21.14 ± 0.5822.00 ± 0.81128 (7)<0.001

daf-16(mu86) Adult life span
TreatmentMeanMedian (censored) versus DMSO (log-rank)

DMSO 11.05 ± 0.3511.00 ± 0.3796 (4)
Quercetin (100 µM)12.64 ± 0.4314.00 ± 0.5194 (6)<0.001
Resveratrol (100 µM)12.01 ± 0.4011.00 ± 0.3897 (3)0.018
TSG (100 μM)12.21 ± 0.4112.00 ± 0.6394 (6)0.02