Review Article

Vitamin A and Retinoids as Mitochondrial Toxicants

Figure 4

A general view of the consequences of in vivo vitamin A supplementation on the susceptibility of mitochondria to ex vivo challenges with different chemical agents. Mitochondria isolated from vitamin A-treated rats are more sensitive to different chemical insults including amyloid β, H2O2, and CaCl2, as discussed in the text.