Research Article

Cardioprotective Effect of Propofol against Oxygen Glucose Deprivation and Reperfusion Injury in H9c2 Cells

Figure 1

Protective effects of propofol on OGD/R induced cytotoxicity in H9c2 cells. (a) Cell viability was assessed by measuring the MTT reduction. Propofol (5, 10, 20, and 50 μM) was adopted during the entire ischemia-reperfusion phase. The viability of ctrl group was defined as 100%. (b) Inhibition of OGD/R induced LDH leakage by propofol. The ctrl group was defined as 100%. (c) Effects of propofol (5, 10, and 20 μM) on OGD/R induced increased intracellular ROS contents in H9c2 cells. (d) Effects of propofol (5, 10, and 20 μM) on OGD/R induced increase in the levels of MDA in H9c2 cells. The results were shown as mean ± SEM from three independent experiments. , versus control, , versus OGD/R treated group without drugs.
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